| Agranulocytosis | · Clozapine |
| Aplastic Anemia | · Chloramphenicol · NSAIDs · Benzene |
| Atropine-like Side Effects | · Tricyclics |
| Cardiotoxicity | · Doxorubicin · Daunorubicin |
| Cartilage Damage in children | · Fluoroquinolones (Ciprofloxacin & Norfloxacin) |
| Cinchonism | · Quinidine |
| Coronary Steal Phenomenon | · Dipyridamole |
| Corneal micro deposits | · Amiodarone |
| Cough | · ACE Inhibitors |
| Diabetes Insipidus | · Lithium |
| Disulfiram-like effect | · Metronidazole · Sulfonylureas (1st generation) |
| Extrapyramidal Side Effects | · Antipsychotics (Thioridazine, Haloperidol, Chlorpromazine) |
| Fanconi’s Syndrome | · Tetracycline |
| Fatal Hepatotoxicity (necrosis) | · Valproic Acid · Halothane · Acetaminophen |
| Gingival Hyperplasia | · Phenytoin |
| Gray Baby Syndrome | · Chloramphenicol |
| Gynecomastia | · Cimetidine · Azoles · Spironolactone · Digitalis · Estrogen & testosterone · INH & ethionamide · Clomiphine · Phenytoin · Reserpine & Methyldopa |
| Hand Foot Syndrome | · 5-Flurouracil (5-FU) |
| Hemolytic Anemia in G6PD-deficiency | · Sulfonamides · Isoniazid · Aspirin · Ibuprofen · Primaquine |
| Hemorrhagic Cystitis | · Cyclophosphamide · Ifosamide (Treat by Mesna & Acetylcysteine Bladder Wash) |
| Hepatitis | · Isoniazid |
| Hot Flashes, Flushing | · Niacin · Tamoxifen · Ca++ Channel Blockers |
| Hypertension: Postural | · Prazocin |
| Hypertension: Rebound | · Clonidine withdrawal |
| Increased intra cranial tension ( ICT) | · Amiodarone · Hypervitaminosis A · OCP’s · Tetracycline · Quinolones |
| Induce CP450 | · Barbiturates · Phenytoin · Carbamazepine · Rifampin |
| Inhibit CP450 | · Cimetidine · Erythromycin · Ketoconazole · Isoniazid (INH) [remember CEKI] |
| Interstitial Nephritis | · Methicillin · NSAIDs (except Aspirin) · Furosemide · Sulfonamides |
| Milk Alkali Syndrome | · Calcium Carbonate (CaCo3) |
| Monday Disease | · Nitroglycerin Industrial exposure ® tolerance during week ® loss of tolerance during weekend ® headache, tach, dizziness upon re-exposure |
| Nephrotoxicity | · Cephaloridine · Gentamycin · Amphotericin |
| Orange Body Fluids | · Rifampin |
| Osteoporosis | · Heparin · Corticosteroids |
| Pancreatitis | · L-Asparginase · Glucocorticoids |
| Photosensitivity | · Lomefloxacin · Pefloxacin |
| Positive Coombs’ Test | · Methyldopa |
| Pulmonary Fibrosis | · Bleomycin · Amiodarone |
| Rabbit Syndrome (Perioral tremors) | · Phenothiazines |
| Red Man Syndrome | · Vancomycin (rapid IV) |
| Severe HTN with Tyramine | · MAOIs |
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Friday, 23 March 2012
DRUG TOXICITIES
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